Cutting-Edge Freezing Technology

We are all eyewitnesses of the overwhelming changes in the development of human eggs and embryos freezing technology. The latest freezing technology has largely replaced traditional slow freezing and has vastly increased thaw survival and success rates, now equally fresh cycles.

The human female egg, as a very large cell mostly composed of fluids, is extremely fragile under all circumstances. When using traditional, slow-freezing technology, ice crystals form slowly in the cell’s cytoplasm, negatively impacting genetic material and cell structural integrity. Using this freezing method results in significant attrition when embryos are thawed—the survival rate is extremely low, around 60%. As eggs are even more fragile than multi-celled embryos, thaw survival rates were even lower for human egg cells. This slow-freezing technology is not a good option for our anxious intended parents and couples.

Up until recently, the new technology named “Vitrification” changed the entire human cell freezing industry. Vitrification is a flash freezing technique that will not bring any damage or crystallization to egg cells as apposed to traditional slow freezing techniques. With vitrification, water is removed from the egg cells and replaced with another agent. After that  the egg cells are cooled in liquid nitrogen at high speed. According to latest research, by using Vitrification techniques, the average survival rates for warmed human egg cells are between 85‰ to 90‰ and when vitrified embryos are warmed, average survival rates are now about 95‰. Thus the majority of highly skilled embryologists, by using vitrification tech, can greatly minimize the formation of ice crystals and keep the cell structure intact,


Then, a new technique called “vitrification” changed the whole human cell-freezing industry. Vitrification is a flash-freezing technique that will not cause damage or crystallization in egg cells, unlike traditional, slow-freezing techniques. With vitrification, water is removed from egg cells and replaced with another agent. Then the egg cells are quickly cooled in liquid nitrogen. According to the latest research using vitrification techniques, average survival rates for warmed human egg cells are between 90% and 94%; when vitrified embryos are warmed, average survival rates are about 95%. Thus, the majority of highly skilled embryologists can minimize formation of ice crystals and keep cell structures intact by using vitrification technology. 


Asian Frozen Eggs has perfected a method for successfully freezing and storing eggs from healthy, young donors, resulting in the premier frozen donor resources. AFE is constantly monitoring the outcome of our frozen-egg technique, and we are always working to improve our pregnancy success rates. We actively pursue laboratory and clinical research to maintain the highest standards in the specialized field of cryobiology. Recent advances in how eggs are frozen and thawed have led to frozen-egg donation becoming a more viable option. Please click Frozen Eggs to see the advantages compared with using fresh eggs.

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