Even for a healthy couple at their peak reproductive age, the chance of pregnancy is only at 20‰ per month under the premise that the female has regular ovulation with open fallopian tubes and the male pattern with normal sperm production. Yes you are right. Only 20‰
Aging is one of the most important factors contributing to women’s infertility. It’s no secret that as you get older, your fertility declines. Women are born with a finite number of eggs, and once they are gone, there is currently no method of producing more. By adolescence, research indicates that 90‰ of the eggs available for ovulation are gone, leaving approximately 100,000 eggs remaining from the original 2 million at birth. Women’s eggs are protected by follicles in ovaries. It is estimated that a woman could only produce about 400 healthy eggs throughout her lifespan. Due to various reasons, many women miss their peak reproductive ages or certain infertility diseases block their way of conceiving a healthy baby. As women age, their eggs also grow older and the quality of eggs decreases, leading to an increasing difficulty in falling pregnant. While men produce fresh sperm every 3 months, the key of fertility treatment for women is to focus on making the best use of whatever they may have left in their ovaries.
Our genetic material is constantly damaged by internal sources such as reactive oxygen species and external sources such as ionizing radiation and sunlight. We seldom notice these injuries because our vital DNA helps to maintain cellular homeostasis. One common factor contributing to infertility is the abnormal numbers of chromosomes in embryos. As we know that constant replication of chromosomes happens when embryonic cells divide. If egg or embryo fails to transfer the right number of chromosomes or complete genetic materials to the son cells, for example loss of a copy of any chromosome, gain of an extra copy of any chromosome, an embryo has three copies for each chromosome, a deletion and/or duplication indicates a piece of a chromosome is lost and /or gained, and so. All above situations result in defective embryos that fail to grow and develop.
The reasons women are impacted by STDs more than men include the fragility of the vagina and the fact that her symptoms are less obvious. When it comes to unprotected sex, women naturally bear more of the consequences than men. Certainly, a man will never become pregnant after sex without a condom, but a woman also might bear, disproportionately, the consequences of sexually-transmitted diseases (STDs). Consider a few sobering facts: untreated STDs cause infertility in at least 24,000 women each year in the U.S. alone. You may be astonished to learn as well that untreated syphilis in pregnant women causes infant death in up to 40 percent of all cases. Finally, when it comes to untreated chlamydia, men suffer neither symptoms nor ill effects most of the time, while women can develop pelvic inflammatory disease which might lead to reproductive system damage. Female factors that affect fertility include the following categories:
|Cervical||Stenosis or abnormalities of the mucus-sperm interaction|
|Uterine||Congenital or acquired defects; may affect endometrium or myometrium; may be associated with primary infertility or with pregnancy wastage and premature delivery|
|Ovarian||Alteration in the frequency and duration of the menstrual cycle—Failure to ovulate healthy egg is the most common infertility problem|
|Tubal||Abnormalities or damage to the fallopian tube; may be congenital or acquired|
|Peritoneal||Anatomic defects or physiologic dysfunctions (eg, infection, adhesions, adnexal masses)|
|Genetic||Chromosomes or genetic abnormalities contribute to infertility and miscarriage|
For intended single or couple who want to be the recipient of donor eggs, choosing frozen or fresh is a tough question. We need to be clear about the difference between using frozen or fresh donor egg and choose 1 plan that fits your situation. Using frozen egg IVF treatment is a much less complicated procedure and please click Frozen Egg to see a range of advantages including no synchronization, immediate availability, more affordability, larger donor pool, less risk, and so.